Abyss could refer to:
- The Abyss - A realm that provides access to all runecrafting altars (with the exception of the astral altar)
- Abyssal Area - An area only accessible through fairy rings with the code ALR
- Abyssal Nexus - An area accessible through fairy rings with the code DIP
- Abyssal whip
- Abyssal tentacle
- Abyssal head
- Abyssal book
- Abyssal bracelet
- Abyssal dagger
- Abyssal bludgeon
- Abyssal guardian
- Abyssal leech
- Abyssal walker
- Abyssal demon
- Abyssal Sire
- Reanimated abyssal
- Enter the Abyss - A miniquest must be completed in order to access the Abyss.
- Lost and Found - A discontinued random event that takes place within the abyssal plane.
- Reanimate Abyssal Creature - A spell found on the Arceuus spellbook.
- The Overseer
- Abyssal orphan
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