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Claws of Guthix is a combat spell in the standard spellbook. Casting it requires a Magic level of 60 in addition to having either a guthix staff or a void knight mace equipped. Casting it uses 1 fire rune, 2 blood runes and 4 air runes each cast. The spell is unlocked by completing the Mage Arena activity; it has to be cast 100 times within the arena itself in order to be used anywhere else. Upon a successful hit, Claws of Guthix lowers the target's Defence by 5%, this decrease does not stack nor will it reapply itself until the opponent returns to their base Defence level. 

By itself, Claws of Guthix has a maximum hit of 20 hitpoints. Like the other God spells, Saradomin Strike and Flames of Zamorak, the spell Charge temporarily increases the maximum hit to 30.

This spell is tied with Flames of Zamorak in price requiring 2 blood runes, 1 fire rune, and 4 air runes. Saradomin Strike costs 2 blood runes, 2 fire runes, and 4 air runes, rendering it the most expensive of the three god spells.

Cost

Spell cost
InputCost
1Fire rune2Blood rune4Air rune759
Combo runes
1Fire rune2Blood rune4Dust rune755
2Blood rune4Air rune1Lava rune758
2Blood rune4Smoke rune1,018
2Blood rune4Air rune1Steam rune822
1Fire rune2Blood rune4Mist rune1,387

Note that since Claws of Guthix requires a Guthix Staff or a Void Knight Mace, rune-providing staves cannot be used. However, a tome of fire can be worn to provide infinite fire runes.


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