|Release date||27 February 2002 (Update)|
|I think this spider has been genetically modified.|
Poison spiders are monsters that can be found in many locations, including the Wilderness. They are aggressive and attack with Melee. These creatures are fairly accurately able to inflict a poison that starts at a 6, and can accurately hit with their attacks. Contrary to popular belief, Protect from Melee does not prevent them from causing poison.
They are generally hated by most players, as they make any location much more difficult to survive in. They are especially irritating to players training on black demons in the Edgeville Dungeon. These creatures pose a threat to players during the Family Crest quest during the battle with Chronozon.
- Edgeville Dungeon
- Observatory Dungeon - The poison spiders here are level 31.
- Taverley Dungeon
- Yanille Agility dungeon
- Lava Maze Dungeon
- Wilderness - South of Callisto's location.
Item Quantity Rarity GE market price Looting bag 1 Uncommon (1/30) Not sold Slayer's enchantment 1 Uncommon  2,982 Mysterious emblem 1 Rare (1/123) 109,568
- ↑ Only dropped by those found in the Wilderness.
- ↑ 2.0 2.1 Only dropped by those found in the Wilderness while on a slayer assignment given by Krystilia.